Inhibitors of cytokinin oxidase derived from 2-(3-phenylureido) benzamide for agricultural use

Short summary
University has developed a novel inhibitors of cytokinin oxidase - stimulators of plant growth and development in optimal and stress conditions applicable in agriculture in plant treatment preparations. The compounds are also suitable for use in plant tissue cultures.

Full description
The present invention relates to derivatives of 2-(3-phenylureido)benzamide, showing the highest known inhibitory activity against cytokinin oxidase/dehydrogenase. As a result, they increase the endogenous cytokinin levels in plants, which leads to their higher viability and higher yield. Application to plants leads to higher yields in both stress and optimal conditions. Treated plants prove increased resistance to stress, such as drought, heat, cold, frost and salinity.
This effect is further streghtened by delay of chlorophyll degradation and plant tissue senescence as an additional effect of the compounds.
Is designed to be used in economically important crops, such as cereals, beet, pomes, drupes and soft fruits, leguminous plants, oil plants, cucumber plants, fibre plants, citrus fruit, vegetables, or plants such as tobacco, nuts, eggplants, sugar cane, tea, vine grapes, hops, bananas and natural rubber and medicinal plants, as well as ornamentals.
Crops include those which have been rendered tolerant towards classes of growth factors by conventional breeding methods or genetic engineering methods.
The compounds are also suitable for use in plant tissue cultures, where they prevent the degradation of cytokinins and thus increase the viability of new plants, regeneration of buds and shoots from explants, callus growth, suppress apical dominance, reduce hyperhydricity of plants grown in vitro and show very strong micropropagation activity.

Contact / source: TOCZ20220428026.pdf - Google Drive